Secreted Protein Sends Signal That Fat Is On The Way

January 12, 2009

After you eat a burger and fries or other fat-filled meal, a protein produced by the liver may send a signal that fat is on the way, suggests a report in the December issue of the journal Cell Metabolism, a Cell Press publication.

Researchers have found in mice that the liver produces a protein called adropin, which rises in response to high-fat foods and falls after fasting. The protein seems to play a role in governing the activity of other metabolic genes, particularly those involved in the production of lipids from carbohydrates. Studies of the protein in obese animals suggest that it also plays a role in insulin response and in preventing the buildup of fat in the liver (a condition known as nonalcoholic fatty liver disease), the researchers said.
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Discovery Of New Signal Pathway Important To Diabetes Research

December 26, 2008

Scientists at Karolinska Institutet and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

The aim of the project was to find out how the healthy body regulates glucose concentrations in the blood. Scientists have known for a long time that glucose is regulated with the help of hormones in the pancreas, which is to say that pancreatic beta cells produce insulin, which reduces sugar levels, and that alpha cells produce glucagon, which boosts them. This glucose balance must be kept within a very narrow interval, and we need both insulin and glucagon to remain in good health.
Read the rest of this entry »


Discovery Of New Signal Pathway Important To Diabetes Research

December 26, 2008

Scientists at Karolinska Institutet and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

The aim of the project was to find out how the healthy body regulates glucose concentrations in the blood. Scientists have known for a long time that glucose is regulated with the help of hormones in the pancreas, which is to say that pancreatic beta cells produce insulin, which reduces sugar levels, and that alpha cells produce glucagon, which boosts them. This glucose balance must be kept within a very narrow interval, and we need both insulin and glucagon to remain in good health.
Read the rest of this entry »


Discovery Of New Signal Pathway Important To Diabetes Research

December 26, 2008

Scientists at Karolinska Institutet and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

The aim of the project was to find out how the healthy body regulates glucose concentrations in the blood. Scientists have known for a long time that glucose is regulated with the help of hormones in the pancreas, which is to say that pancreatic beta cells produce insulin, which reduces sugar levels, and that alpha cells produce glucagon, which boosts them. This glucose balance must be kept within a very narrow interval, and we need both insulin and glucagon to remain in good health.
Read the rest of this entry »


Discovery Of New Signal Pathway Important To Diabetes Research

December 26, 2008

Scientists at Karolinska Institutet and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

The aim of the project was to find out how the healthy body regulates glucose concentrations in the blood. Scientists have known for a long time that glucose is regulated with the help of hormones in the pancreas, which is to say that pancreatic beta cells produce insulin, which reduces sugar levels, and that alpha cells produce glucagon, which boosts them. This glucose balance must be kept within a very narrow interval, and we need both insulin and glucagon to remain in good health.
Read the rest of this entry »


Discovery Of New Signal Pathway Important To Diabetes Research

June 4, 2008

Scientists at Karolinska Institutet and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

The aim of the project was to find out how the healthy body regulates glucose concentrations in the blood. Scientists have known for a long time that glucose is regulated with the help of hormones in the pancreas, which is to say that pancreatic beta cells produce insulin, which reduces sugar levels, and that alpha cells produce glucagon, which boosts them. This glucose balance must be kept within a very narrow interval, and we need both insulin and glucagon to remain in good health.
Read the rest of this entry »