New Hope For HIV-1 Eradication From ‘Shock And Kill’ Research

June 6, 2009

Latent HIV genes can be ‘smoked out’ of human cells. The so-called ‘shock and kill’ technique, described in a preclinical study in BioMed Central’s open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS.

Dr. Enrico Garaci, president of the Istituto Superiore di Sanità (the Italian Institute of Health) and Dr. Andrea Savarino, a retrovirologist working at the institution, worked with a team of researchers to study the so-called “barrier of latency” which has been the main obstacle to HIV eradication from the body.
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New Hope For HIV-1 Eradication From ‘Shock And Kill’ Research

June 6, 2009

Latent HIV genes can be ‘smoked out’ of human cells. The so-called ‘shock and kill’ technique, described in a preclinical study in BioMed Central’s open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS.

Dr. Enrico Garaci, president of the Istituto Superiore di Sanità (the Italian Institute of Health) and Dr. Andrea Savarino, a retrovirologist working at the institution, worked with a team of researchers to study the so-called “barrier of latency” which has been the main obstacle to HIV eradication from the body.
Read the rest of this entry »


ZIOPHARM Presents Positive Data From Phase I Study Of Palifosfamide In Combination With Doxorubicin At ASCO

June 3, 2009

ZIOPHARM Oncology, Inc. (Nasdaq: ZIOP) announced that it presented final data from a Phase I study of palifosfamide (ZymafosTM) in combination with doxorubicin at the 45th Annual American Society of Clinical Oncology (ASCO) meeting held in Orlando, FL, May 29th to June 2nd.

The Phase I trial of palifosfamide in combination with doxorubicin was fully enrolled with 13 patients, predominantly with soft tissue sarcoma and non-small cell lung cancer, and who had received a median of two prior therapies. Of 12 evaluable patients, there were 3 partial responses. Of the 8 patients with soft tissue sarcoma (STS) 75 percent had stable disease or better, with 2 having partial responses and 4 having prolonged stable disease. The median progression free survival (PFS) was 19 weeks.
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Individuals Genetically At Risk Of Developing Psychological Disorders Also Benefit The Most From Positive Environments

May 31, 2009

Certain individuals have long been regarded as particularly susceptible to developing behavioural and emotional problems when they experience negative environmental conditions, due to the fact that they carry so-called ‘vulnerability genes’. Existing research suggests, for instance, that such ‘genetically vulnerable’ individuals are most likely to become impulsive and hyperactive if their mothers smoked while pregnant, to behave anti-socially if subjected to child abuse, and to become depressed if exposed to many negative life events (e.g., divorce, unemployment). But a new evaluation of existing gene-by-environment interaction (GXE) research highlighting such genetic vulnerability to adversity challenges this traditional interpretation of existing evidence. Research published in Molecular Psychiatry suggests that those carrying ‘vulnerability genes’ are not only more likely than others to be adversely affected by negative experiences but to also benefit more than others from positive environments, making them more malleable or plastic, not just vulnerable. This novel interpretation of old and new findings suggests that ‘vulnerability genes’ might be better conceptualised as ‘plasticity or malleability genes’ because carriers are more affected, for better and for worse, by positive and negative environmental conditions.
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U.S. Bill Would Establish Survey To Collect Health Data From Native Hawaiians, Pacific Islanders

May 28, 2009

Madeleine Bordallo, the U.S. delegate from Guam, has introduced legislation that would fund a survey to collect health data from Native Hawaiians and Pacific Islanders, the Pacific Daily News reports. The legislation would amend the Public Health Service Act to fund the survey through HHS.

Bordallo said, “Native Hawaiian and Pacific Islander communities are eager to move forward with their efforts to improve public health. This scientific survey would establish baseline health information to inform health policy and interventions so that individual and community health can be properly tracked and evaluated.”
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U.S. Bill Would Establish Survey To Collect Health Data From Native Hawaiians, Pacific Islanders

May 28, 2009

Madeleine Bordallo, the U.S. delegate from Guam, has introduced legislation that would fund a survey to collect health data from Native Hawaiians and Pacific Islanders, the Pacific Daily News reports. The legislation would amend the Public Health Service Act to fund the survey through HHS.

Bordallo said, “Native Hawaiian and Pacific Islander communities are eager to move forward with their efforts to improve public health. This scientific survey would establish baseline health information to inform health policy and interventions so that individual and community health can be properly tracked and evaluated.”
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Sandra R. Gordon Wins Golden Trumpet Award From The Publicity Club Of Chicago

May 27, 2009

At the 50th Annual Trumpet Awards Luncheon at the Palmer House Hilton in Chicago, Sandra R. Gordon received one of the most coveted public relations awards from the Publicity Club of Chicago (PCC). As the director of public relations at the American Academy of Orthopaedic Surgeons (AAOS), Sandra was the lead visionary and creative force for their organization’s multi-faceted special event “Seventy-five Years of Orthopaedic Surgery”.
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