New Hope For HIV-1 Eradication From ‘Shock And Kill’ Research

Latent HIV genes can be ‘smoked out’ of human cells. The so-called ‘shock and kill’ technique, described in a preclinical study in BioMed Central’s open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS.

Dr. Enrico Garaci, president of the Istituto Superiore di Sanità (the Italian Institute of Health) and Dr. Andrea Savarino, a retrovirologist working at the institution, worked with a team of researchers to study the so-called “barrier of latency” which has been the main obstacle to HIV eradication from the body.

New Hope For HIV-1 Eradication From ‘Shock And Kill’ Research

Latent HIV genes can be ‘smoked out’ of human cells. The so-called ‘shock and kill’ technique, described in a preclinical study in BioMed Central’s open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS.

Dr. Enrico Garaci, president of the Istituto Superiore di Sanità (the Italian Institute of Health) and Dr. Andrea Savarino, a retrovirologist working at the institution, worked with a team of researchers to study the so-called “barrier of latency” which has been the main obstacle to HIV eradication from the body.

FDA approval of Synthroid

Question:

More than seven years ago I read that synthroid had never been approved by the FDA. I emailed the company that makes synthroid and asked them about this. They replied saying that is was true that they had never been approved, but that they stood behind their product. Just recently I emailed the FDA about the approval of synthroid and they said that it was approved Sept. 2002. I`ve been on synthroid since 1982. For twenty years I was on an unapproved medication. Who do we trust?

Modifiable Hip Fracture Complications Contribute To Mortality, Institute For Aging Research Finds

Potentially modifiable post-fracture complications, including pneumonia and pressure ulcers, are associated with an increased risk of death among nursing home residents who have suffered a hip fracture, according to a new study conducted by scientists at the Institute for Aging Research at Hebrew SeniorLife.

“Prevention strategies to reduce pressure ulcers and pneumonia may help reduce mortality in this frail population,” says lead author Sarah D. Berry, M.D., M.P.H., a research fellow at the Institute and a staff geriatrician at Hebrew Rehabilitation Center.

Age Concern And Help The Aged On New Research On Dementia, UK

Commenting on the new research on Alzheimer’s by the the Institute of Psychiatry at King’s College London, Michelle Mitchell, Charity Director for Age Concern and Help the Aged said:

‘This research provides more scientific evidence that working is a crucial ingredient of that engaging and active lifestyle we know is key to healthy mental ageing.

‘Ensuring a more comfortable retirement is not the only reason why older workers want to work for longer. Keeping their brains active and their social relationships fresh are often equally important.

The End Of The Line For Existing Stem Cell Research?

Time is short for scientists to respond to the call for comments on the National Institutes of Health (NIH) proposed guidelines for the use of human embryonic stem (ES) cell lines and their eligibility for federal funds. On May 26, the window to provide feedback will close, and the drafted rules leave the possibility that funding for almost all existing cell lines will disappear.

In a Forum article published online on May 14 by Cell Press in the journal

HHS Names Federal Coordinating Council For Comparative Effectiveness Research

The U.S. Department of Health and Human Services announced the members of the Federal Coordinating Council for Comparative Effectiveness Research. Authorized by the American Recovery and Reinvestment Act (ARRA), the new council will help coordinate research and guide investments in comparative effectiveness research funded by the Recovery Act.

“Comparative effectiveness research can improve care for all Americans and is an important element of President Obama’s health reform plan,” said HHS Spokeswoman Jenny Backus. “President Obama is committed to openness and transparency and the Coordinating Council will host open meetings and a listening session as it begins its important work.”

Alessandro Riva Receives IADR Salivary Research Award

Professor Alessandro Riva, University of Cagliari, Italy, is the recipient of the 2009 Salivary Research Award from the International Association for Dental Research (IADR), to be presented at its 87th General Session & Exhibition in Miami, Florida, USA, on April 1, 2009.

Prof. Riva is head of the Department of Cytomorphology at the University of Cagliari. After completing his medical training and one year in the Department of Anatomy, St. Thomas’ Hospital, London, he joined the Department of Anatomy in Cagliari. He has been the chair in anatomy since 1971.

Cause Of Cartilage Degeneration In Osteoarthritis Discovered By Scripps Research Scientists

The scientists describe their work in this week’s Early Edition of the Proceedings of the National Academy of Sciences. In the study, the team shows how the loss of the protein HMGB2, found in the surface layer of joint cartilage, leads to the progressive deterioration of the cartilage that is the hallmark of osteoarthritis.

“We have found the mechanism that begins to explain how and why aging leads to deterioration of articular cartilage,” says Scripps Research Professor Martin Lotz, M.D., a world-renowned arthritis researcher who led the study with Noboru Taniguchi, M.D., Ph.D., a senior research associate in his lab. “Our findings demonstrate a direct link between the loss of this protein and osteoarthritis.”

Special Issue Of Lymphatic Research And Biology Honors Judah Folkman, M.D

Dedicated to the memory and scientific accomplishments of Dr. Judah Folkman, who pioneered the fields of angiogenesis and vasculogenesis and shed light on the link between blood supply and neoplastic disease, the newly released special double issue (Volume 6, Number 3-4) of Lymphatic Research and Biology includes a series of papers that reflect the research impact of one of the pre-eminent physician-scientists of his generation. Lymphatic Research and Biology